April 29, 2005
Obesity and Dementia

Middle-Age Obesity Linked to Dementia in Later Life [Story.]

Ok, how obese to you have to be and how much more likely are you to get dementia? Surprisingly, the article cited above actually gives us most of the needed facts:

Investigators analyzed data for 10,276 members of Kaiser Permanente medical care program in California who underwent detailed health checks from 1964 to 1973 when they were aged 40-45 and who were still members of the health plan in 1994.

In 1994, dementia was diagnosed in 713 (7 percent) participants. [RL: Hurray! They give us something like a baseline risk here.] Obese people (body mass index 30 or above) were 74 percent more likely to have dementia, while overweight people (body mass index 25-29.9) were 35 percent more likely to have dementia compared with those of normal weight (body mass index 18.6-24.9). [RL: Roughly speaking this seems to mean that someone with normal weight is about 5% likely to get dementia and an obese person is about 9% likely to get it. (UPDATE: My calculations are wrong here but you get the idea.) Is this increase big or small? I dunno.]

Body mass index predicted dementia more strongly among women. For example, obese women were 200 percent more likely to have dementia than women of normal weight, while obese men had a non-significant 30 percent increase in risk. [RL: At least they didn't disregard the 30 percent figure just because it was "non-significant" in a statistical sense.]

Both men and women with the highest skin-fold measurements had a 60-70 percent greater risk of dementia compared to those with the lowest measurements.

Posted by Robert Lawson at 11:19 AM in Science  ·  TrackBack (90)

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